The Rough Collie's natural unexaggerated form has protected it from many of the inherited conditions which plague some dog breeds.

However like all species, including our own, it is susceptible to a few inherited conditions, which responsible breeders endeavour to minimize as much as possible by the careful monitoring and selection of breeding stock.

SPAY/NEUTER AND JOINT DISEASE

April 2014 - Confirmed Lungworm Death in Ayrshire, Scotland - Click HERE for more information

Statement from the KC - March 2014

Recording CEA and prcd-PRA DNA tests
The Kennel Club would wish to clarify the position with regard to the recording of DNA test results for both prcd-PRA and CEA/CH.

Both these DNA tests carry patents in the UK and most other European countries. The patents are owned by Cornell University in the US, and are licensed exclusively to OptiGen worldwide. They also have non-exclusive licensing of the CL test (for Border Collies) in Europe (and exclusive use of this patent in the USA). It is important to note therefore that the KC will only officially record the DNA results for these diseases if they have been tested by OptiGen (or Genetic Technologies in Australia who have a licence to perform the tests).

Part of the patent includes the advertisement and recording of results and therefore whilst this patent is still in force, the Kennel Club will only be publishing the outcome of Optigen tests. The position the KC has taken stems purely from legal ramifications and has no reason to question the quality and reliability of tests offered by other labs. For clarification, only results of prcd-PRA or CEA/CH DNA tests issued by Optigen will be recorded by the KC, and these results will appear on registration certificates, in the BRS and online via Mate Select.

However, we are aware that other laboratories such as Laboklin and Idexx have made arrangements with Optigen so that if any of their clients want either prcd-PRA or CEA/CH results recorded, these labs will send the DNA to Optigen and they will issue a result / certificate back to laboratory.



You can report a suspected adverse reaction or lack of efficacy to a veterinary medicine by clicking on the banner below - this will take you to the online reporting site. This scheme is run by the VMD's Pharmacovigilance Unit and is used to collect information from veterinary professionals and the general public on suspected adverse reactions and lack of efficacy to veterinary medicines. We collect reports on both licensed and unlicensed veterinary medicines, and human medicines used to treat animals under the cascade. The information that you provide can help to improve the safe and effective use of veterinary medicines.

Many herding breed dogs (the most commonly affected in the UK are: All breeds of Collie, Shetland Sheepdog, GSD and, Australian Shepherd dogs - including cross breeds) have a genetic predisposition to adverse drug reactions involving over a dozen different drugs.

The most serious adverse drug reactions involve several antiparasitic agents, Ivermectin, Milbemycin (and related drugs), the antidiarrheal agent Loperamide (Imodium), and several anticancer drugs (Vincristine, and Doxorubicin, plus several others). These drug sensitivities result from a mutation in the multidrug resistance gene (MDR1 gene).

MDR1
(PDF Downloads)

LIST OF DRUGS

FACTSHEET

LIST OF DRUGS THAT CAUSE SENSITIVITY TO DOGS WITH MDR1 MUTATION

Class A DO NOT use these drugs in dogs with the MDR1 Gene Defect

Ivermectine substances "Anti parasites": (Diapec®, Ecomectin®, Equimax®, Eqvalan®, Ivomec®, Noromectin®, Paramectin®, Qualimec®, Sumex®, Virbamec®) 

Doramectine substances "Anti parasites":  (Dectomax® )

Loperamide substances "ant diarrheal ": (Imodium®)

Moxidectine substances "Anti Parasites" (Cydectin®, Equest®) 

(Flagyl )

Class B

Use only under close control of veterinarian

Cytostatics  "Chemotherapy": (Vinblastine, Vincristine, Doxorubicine, Paclitaxel, Docetaxel, Methotrexat, Vincristine)

Immunosuppressive: (Cyclosporine A)

Heart glycosides: (Digoxine, Methyldigoxine)

Opioids: (Morphium)

Antiarrhythmics: (Verapamil, Diltiazem, Chinidine)

Antiemetics (Ondansetron, Domperidon, Metoclopramide )

Antibiotics (Sparfloxacin, Grepafloxacin, Erythromycin)

Antihistamin (Ebastin)

Glucocorticoid (Dexamethason)

Acepromazine (tranquilizer and pre-anesthetic agent) *

Butorphanol "analgesic and pre-anesthetic agent" *

Other drugs: Etoposide, Mitoxantrone, Ondansetron, Paclitaxel, Rifampicin 

Class C Can be used only in the permitted application form and dose Selamectin (Stronghold®), Milbemax®  and Advocate® .

 

List of Eye Panel Examiners
(pdf document)